Current biology research relies on the ability to purify cell types using antibodies or transgenic constructs. However, antibody availability is often limited, and genetic manipulation is labor intensive or sometimes impossible. To date, no universal method exists to enrich for cell types without a priori knowledge of cell type markers. Here, we propose GateID, a computational method that combines single-cell transcriptomics with FACS index sorting to purify cell types using only native cellular properties.
from Top Technology News -- ScienceDaily https://ift.tt/31NGVpu
Thursday 3 October 2019
New method to purify cell types to high purity
Posted By: Unknown - October 03, 2019About Unknown
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